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|a 10.1016/c2011-0-06857-6
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|0 (IdRef)122689283
|1 http://www.idref.fr/122689283/id
|a Zhao, Huimin.
|4 edt.
|e Éditeur scientifique
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|a Synthetic Biology
|h [Ressource électronique] :
|b Tools and Applications
|c edited by Huimin Zhao,....
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|a Données textuelles.
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|a San Diego, CA :
|b Elsevier Science,
|c 2013.
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|b txt
|2 rdacontent
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|a Titre provenant de la page de titre du document numérique.
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|a Numérisation de l'édition de San Diego : Elsevier Science & Technology Books, 2013.
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|a Date de publication et éditeur d'après le site du fournisseur.
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|a La pagination de l'édition imprimée correspondante est de : xviii, 333 p.
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|a Notice rédigée d'après la consultation du 2014-03-14.
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|a L'impression du document génère 351 p.
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|a Bibliographie en fin de chapitre. Index.
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|a L'accès complet à la ressource est réservé aux usagers des établissements qui en ont fait l'acquisition
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|a Fichier PDF.
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|a Synthetic Biology provides a framework to examine key enabling components in the emerging area of synthetic biology. Chapters contributed by leaders in the field address tools and methodologies developed for engineering biological systems at many levels, including molecular, pathway, network, whole cell, and multi-cell levels. The book highlights exciting practical applications of synthetic biology such as microbial production of biofuels and drugs, artificial cells, synthetic viruses, and artificial photosynthesis. The roles of computers and computational design are discussed, as well as future prospects in the field, including cell-free synthetic biology and engineering synthetic ecosystems. Synthetic biology is the design and construction of new biological entities, such as enzymes, genetic circuits, and cells, or the redesign of existing biological systems. It builds on the advances in molecular, cell, and systems biology and seeks to transform biology in the same way that synthesis transformed chemistry and integrated circuit design transformed computing. The element that distinguishes synthetic biology from traditional molecular and cellular biology is the focus on the design and construction of core components that can be modeled, understood, and tuned to meet specific performance criteria and the assembly of these smaller parts and devices into larger integrated systems that solve specific biotechnology problems. Includes contributions from leaders in the field presents examples of ambitious synthetic biology efforts including creation of artificial cells from scratch, cell-free synthesis of chemicals, fuels, and proteins, engineering of artificial photosynthesis for biofuels production, and creation of unnatural living organisms. Describes the latest state-of-the-art tools developed for low-cost synthesis of ever-increasing sizes of DNA and efficient modification of proteins, pathways, and genomesHighlights key technologies for analyzing biological systems at the genomic, proteomic, and metabolomic levels which are especially valuable in pathway, whole cell, and multi-cell applications. Details mathematical modeling tools and computational tools which can dramatically increase the speed of the design process as well as reduce the cost of development
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|a Nécessite un lecteur de fichier PDF.
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|b Section I: Synthesis and Engineering Tools in Synthetic Biology
|c Chapter 1 - New Tools for Cost-Effective DNA Synthesis
|c Chapter 2 - Protein Engineering as an Enabling Tool for Synthetic Biology
|c Chapter 3 - Pathway Engineering as an Enabling Synthetic Biology Tool
|c Chapter 4 - From Biological Parts to Circuit Design
|b Section II: Computational and Theoretical Tools in Synthetic Biology
|c Chapter 5 - Theoretical Considerations for Reprogramming Multicellular Systems
|c Chapter 6 - Computational Protein Design for Synthetic Biology
|c Chapter 7 - Computer-Aided Design of Synthetic Biological Constructs with the Synthetic Biology Software Suite
|c Chapter 8 - Computational Methods for Strain Design
|b Section III: Applications in Synthetic Biology
|c Chapter 9 - Design and Application of Synthetic Biology Devices for Therapy
|c Chapter 10 - Drug Discovery and Development via Synthetic Biology
|c Chapter 11 - Synthetic Biology of Microbial Biofuel Production: From Enzymes to Pathways to Organisms
|c Chapter 12 - Tools for Genome Synthesis
|c Chapter 13 - Synthetic Microbial Consortia and their Applications
|b Section IV: Future Prospects
|c Chapter 14 - Semi-Synthetic Minimal Cells: Biochemical, Physical, and Technological Aspects
|c Chapter 15 - Transforming Synthetic Biology with Cell-Free Systems
|c Chapter 16 - Towards Engineered Light-Energy Conversion in Nonphotosynthetic Microorganisms
|c Chapter 17 - Applications of Engineered Synthetic Ecosystems
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|a Bioengineering.
|2 lc
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|a Synthetic biology.
|2 lc
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|0 (IdRef)099557169
|1 http://www.idref.fr/099557169/id
|a Biologie de synthèse.
|2 ram
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|u https://srvext.uco.fr/login?url=https://univ.scholarvox.com/book/88814467
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